[Biofilms in otolaryngology].

Biofilms in Otolaryngology

Effectiveness of honey on Staphylococcus aureus and Pseudomonas aeruginosa biofilms.

OBJECTIVES Biofilms formed by Pseudomonas aeruginosa (PA) and Staphylococcus aureus (SA) have been shown to be an important factor in the pathophysiology of chronic rhinosinusitis (CRS). As well, honey has been used as an effective topical antimicrobial agent for years. Our objective is to determine the in vitro effect of honey against biofilms produced by PA and SA. STUDY DESIGN In vitro tes...

Eradicating chronic ear, nose, and throat infections: a systematically conducted literature review of advances in biofilm treatment.

OBJECTIVE Bacteria can grow as individual, planktonic organisms or as complex biofilm communities that are more resistant to treatment. This review was designed to systematically search to identify recent laboratory studies on eradication of biofilms in otolaryngologic infections to highlight promising advances in biofilm treatment. DATA SOURCES A systematic electronic literature search of Me...

Grand Challenges in Pediatric Otolaryngology

IntroductIon The field of pediatric otolaryngology has undergone significant changes over the past two decades. These changes have resulted in new areas of investigations and challenges. This article will summarize some of the more recent advances and challenges facing this field. Specific focus of this grand challenge will include: (1) Role of biofilms in infectious diseases in otolaryngology,...

Biofilm formations in nasopharyngeal tissues of patients with nasopharyngeal osteoradionecrosis.

OBJECTIVE Determine the presence of nasopharynx biofilms in patients with nasopharyngeal cancer (NPC) and osteoradionecrosis (ORN) and patients with NPC but no ORN. STUDY DESIGN Cross-sectional study. SETTING Tertiary referral medical center. SUBJECTS AND METHODS We enrolled 27 patients with NPC from our outpatient clinic during January 2010 to June 2012. These patients were diagnosed wit...